Thalassemia major " Cooley's anaemia "
 |
| Thalassemia major " Cooley's anemia " |
- Beta-thalassemia refers to inherit the group of blood disorders characterized by a reduction or absence of the beta chain of globulin in haemoglobin syntheses.
- Haemoglobin b-thalassemia is the most severe of the b-thalassemia syntheses and is known as thalassemia major or cooleys anaemia.
Etiology :
- Genetically determined inherited disease.- The autosomal recessive pattern of inheritance.
Incidence :
- Most prevalent in the Mediterranean, Middle East, India, Pakistan, Southeast, Asia and Africa.Prognosis :
- No known cure.- often fatal in late childhood or early adolescent.
Preventive measures :
- Parents of a child with thalassemia should be tested for the trait and referred for genetic counselling.- Prenatal diagnosis terminates pregnancy .
Clinical manifestations :
- Insidious onset at the end of the 1st year of the life.- Pallor, poor feeding, protuberant abdomen due to hepatosplenomegaly, headache, bone pain, exercise intolerance and easy fatigability and growth retardation.
Complications :
1. Splenomegaly and hepatomegaly due to extramedullary hemopoiesis and rapid destruction of RBCs. coagulation abnormalities.2. Growth and endocrine complications :
- Growth retardation.
- Diabetes in older children due to iron deposition in the pancreas.
- Adrenal and pituitary dysfunction.
3. skeletal complication :
- Maxillary hypertrophy.
- Broad ribs.
- Skeletal osteoporosis.
4. Cardiac complication :
- Arrhythmia, pericarditis, congestive heart failure " the usual cause of death of thalassemics ".
5. Skin :
- Brownish discolouration due to iron deposition.
- Jaundice.
Treatment :
- Frequent and regular blood transfusion to maintain haemoglobin level above 9-10 gm/ dl.- Packed RBCs usually used.
- Iron chelating agent to reduce the toxic side effects of excess iron " hemosiderosis ".
- E.g. deferoxamine: desferal.
- Folic acid.
- Splenectomy in huge hypersplenism.
- Bone marrow transplantation.
READ MORE:
Chickenpox And Diphtheria
Polyhydramnios And Oligohydramnios
Congenital Dislocation Of The Hip CDH
I can’t believe this is really true I never believe there is cure to this hsv 2 because all the hospital have told me there is no cure to it, few months ago I saw this man email DR.AZIEGBE on internet from a testimony share by someone who he help with his herbal cure I contact his email and ask for his help also, that is how he inform me about the cure process and this man sent me a herbal medicine which I took according to the way he instructed for 2 week I can’t believe when I go for test my result come out negative i am so happy to share this to the world there is real cure to herpes you can also contact DR.AZIEGBE through his email now DRAZIEGBE1SPELLHOME@GMAIL. COM and also WhatsApp him +2349035465208. or my assistant my email: JAMESAVA0001@GMAIL. COM... He also have herbs medicine to cured the following diseases;
ReplyDeleteDiabetes, Lupus, HPV, Gout, Hepatitis A,B, Infertility, HIV/AIDS, CANCER, WART
I can’t believe this is really true I never believe there is cure to this hsv 2 because all the hospital have told me there is no cure to it, few months ago I saw this man email DR.AZIEGBE on internet from a testimony share by someone who he help with his herbal cure I contact his email and ask for his help also, that is how he inform me about the cure process and this man sent me a herbal medicine which I took according to the way he instructed for 2 week I can’t believe when I go for test my result come out negative i am so happy to share this to the world there is real cure to herpes you can also contact DR.AZIEGBE through his email now DRAZIEGBE1SPELLHOME@GMAIL. COM and also WhatsApp him +2349035465208. or my assistant my email: JAMESAVA0001@GMAIL. COM... He also have herbs medicine to cured the following diseases;
ReplyDeleteDiabetes, Lupus, HPV, Gout, Hepatitis A,B, Infertility, HIV/AIDS, CANCER, WART
I am here to give my testimony about Dr Ebhota who helped me.. i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by salami, i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Dr Ehbota cured them. when i contacted him he gave me hope and send a Herbal medicine to me that i took for just 2 weeks and it seriously worked for me, my HERPES result came out negative. I am so happy as i am sharing this testimony. My advice to you all who thinks that there is no cure for herpes that is Not true just contact him and get cure from Dr Ebhota healing herbal cure of all kinds of sickness you may have like (1) CANCER,(2) DIABETES,(3) HIV&AIDS,(4) URINARY TRACT INFECTION,(5) CANCER,(6) IMPOTENCE,(7) BARENESS/INFERTILITY(8) DIARRHEA(9) ASTHMA(10)SIMPLEX HERPES AND GENITAL(11)COLD SOREHERPES. he also cure my friend from cervical cancer Email: drebhotasoultion@gmail.com or whatsapp him on +2348089535482
ReplyDeleteI am here to give my testimony about Dr Ebhota who helped me.. i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by salami, i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Dr Ehbota cured them. when i contacted him he gave me hope and send a Herbal medicine to me that i took for just 2 weeks and it seriously worked for me, my HERPES result came out negative. I am so happy as i am sharing this testimony. My advice to you all who thinks that there is no cure for herpes that is Not true just contact him and get cure from Dr Ebhota healing herbal cure of all kinds of sickness you may have like (1) CANCER,(2) DIABETES,(3) HIV&AIDS,(4) URINARY TRACT INFECTION,(5) CANCER,(6) IMPOTENCE,(7) BARENESS/INFERTILITY(8) DIARRHEA(9) ASTHMA(10)SIMPLEX HERPES AND GENITAL(11)COLD SOREHERPES. he also cure my friend from cervical cancer Email: drebhotasoultion@gmail.com or whatsapp him on +2348089535482
ReplyDeleteI have bookmarked your blog, the articles are way better than other similar blogs.. thanks for a great blog!
ReplyDeletehttps://touchofhealthmedical.com/
Thanks for your post. I’ve been thinking about writing a very comparable post over the last couple of weeks, I’ll probably keep it short and sweet and link to this instead if thats cool. Thanks. what is cultured ghee
ReplyDeleteIt is perfect time to make some plans for the future and it is time to be happy. I've read this post and if I could I desire to suggest you some interesting things or suggestions. Perhaps you could write next articles referring to this article. I want to read more things about it! testogen
ReplyDeleteI would like to thank Ultimate Life Clinic for reversing my father's Amyotrophic Lateral Sclerosis (ALS). My father’s ALS condition was fast deteriorating before he started on the ALS Herbal medicine treatment from Ultimate Life Clinic. He was on the treatment for just 6 months and we never thought my father will recover so soon. He has gained some weight in the past months and he is able to walk with no support. You can reach them through there website www.ultimatelifeclinic.com
ReplyDeleteDo You Need A Powerful Africa Native Doctor? I Mean A Spiritual Herbalist
ReplyDeleteWith Great Spirit Connected To Ancestors. Call or WhatsApp +2349058774809 Dr Obodubu Monday Is A High Voodoo Priest Master. He is a Spell Caster, Native
Doctor, Spiritual Herbalist, Powerful Sickle cell Healer, Spiritual
Astrologer, Psychic Reader, Multi Guru, Witch Doctor, Priest Of Africa
Money Ritual.
Have You Been To Native Doctor to Native Doctor Without Any Solution To
Your Problems Or Rather Add To it? Have You Been To Place To Place In View
Of A Powerful Native Doctor That Can Solve All Your Predicament, You Must
Understand That There Is A Native Doctor That Supersede All Native Doctor
Among All Native Doctor, If You Are In Search Of A Powerful Native Doctor
With Great Spiritual Powers, Then You Must Be In Search Of A Native Doctor
That Derives Power From The Marine World. That Is The Spirituality Of The
Greatest Africa Native Doctor Obodubu.
Dr Obodubu Is Recognized All Over The World Of Marine Kingdom, As One
Of The Top Fortunate And Most Powerful Native Doctor Of Charms Casts From
The Beginning Of His Ancestors ship Until Now Dr who lives Strong
Among All Other Native Doctors, There Have Never Been Any Form Of
Impossibility Beyond The Control Of Dr Obodubu. It Doesn't Matter The
Distance Of The Person With The Problems Or Situation, All You Have To Do
Is Believe
In The Native Obodubu charms Casts That Works, He Always
Warns Never To Get His Charms Casts If You Do Not Believe Or Unable To
Follow His Instruction.
It Is The Assignment Of The Native Doctor Obodubu To Offer
Services To Those In Need Of Spiritual Assistance Not Minding The Gravity
Of Your Situations Or Distance As Long As Water, Sea, Ocean, Lake, River
Sand etc. Are Near You, Then Your Problems Of Life Would Be Controlled
Under Your Foot.
If You Need Any Spiritual Help On Any of These:
Get Your Lover Back
Fruit Of The Womb
Fibroid
Business Boom
Financial Breakthrough
Get Rich Without Ritual WhatsApp +2349058774809
Do As I Say
Bad Dream
Promise And Fail
Epilepsy
Spiritual Attack
Land/Court Case
Mental Disorder
Political Appointment
Visa Approval
Cancer
Examination Success
Spend And Get Back
Good Luck
Natural Health
Hypertension
Diabesity (Diabetic+Obesity
Stroke
Sickle Cell
Impotency
Win Court Case
Promotion At Work
Commanding Tone
Protection Ring
Marriage Success
Love Ring
Favour Ring
Recover Lost Glory
Spiritual Power For Men Of God
Travel Success Ring
Job Success
Lotto/Pool Win And Many More.
Make Haste To Call or WhatsApp Dr Obodubu Monday +2349058774809. Or Mail Him to
babadoctorobodubuspiritualhome@gmail.com For Spiritual Problem Today And
You Will Surely
Get Solution To All Your Predicament.
Email: babadoctorobodubuspiritualhome@gmail.com
ReplyDeleteGET YOUR EX LOVER BACK OR YOUR BROKEN RELATIONSHIP OR MARRIAGE RESTORED BACK.
Greatest things I have experienced in my life and my broken marriage. and I saw a wonderful testimony of Lisa on a psychic page about the good works of DR Owo. I never believed it, because I have never heard anything about such a miracle before. Nobody would have been able to convince me about it not until DR Owo did a marvelous work for me that restored my broken marriage by getting my husband back to me and leaving the other woman he wanted to marry. as his new wife after fixing their wedding date. I was truly shocked when my husband knelt down pleading for forgiveness for me to accept him back. I am really short of words to use to show my appreciation to Dr Owo For his a God sent to me and my Entire family for divine restoration of my marriage. Contact him now for any kind of help via email: drowoherbs@gmail.com
This has really worked and I am proud to testify of it. I saw a post on how a lady got cured from herpes by Dr Ajayi . I suffer from herpes 2 years ago and i have used different drugs given to me by my doctor but noon of this drugs cure me from herpes, I did a research on the internet on how to get cure from herpes and there i saw a lady testifying of how Dr Ajayi helped her cured her herpes. Although I never believed in herbal medicine I reluctantly tried him because I was desperate and i contact him and explain my problems to him, he told me not to worry that he is going to help me cure my herpes after 2 days he sent me his herbal medicine which i took for 14 days, to my greatest surprise Dr Ajayi helped me cure my herpes, am grateful sir. Are you also suffering from herpes or any diseases and viruses Dr Ajayi can help cure your herpes and He can also cure diseases like HIV/AIDS, Hepatitis, Lupus, Cancer, E.T.C Email him for urgent help at ajayiherbalhome@gmail.com Visit his website https://ajayiherbalhome.weebly.com you can also call or whatsapp him +2348154724883. Thank you Dr Ajayi for the help...
ReplyDeleteHerpes is a sexually transmitted virus that primarily infects the mouth and the genitals. It is transmitted by bodily fluids – penetration isn’t required for transmission, oral-oral or oral-genital contact will suffice, There are two types of herpes simplex virus: HSV-1 and HSV-2. Both virus types can cause sores around the mouth (herpes labialis) and on the genitals (genital herpes).You can purchase herbs from www.facebook.com/DrOdiathenaturopathic/ He has a cure for Herpes. Cold sores are caused by the herpes simplex virus (HSV). Cold sores sometimes called fever blisters, are groups of small blisters on the lip and around the mouth. The skin around the blisters is often red, swollen, and sore. The blisters may break open, leak a clear fluid, and then scab over after a few days. They usually heal in several days to 2 weeks. The herpes simplex virus usually enters the body through a break in the skin around or inside the mouth. It is usually spread when a person touches a cold sore or touches infected fluid—such as from sharing eating utensils or razors, kissing an infected person, or touching that person's saliva. A parent who has a cold sore often spreads the infection to his or her child in this way. Cold sores can also be spread to other areas of the body. Luckily there is a cure for herpes Contact Dr Odia Via:(drodiaherbalistcenter@gmail.com)
ReplyDelete